BDBM165065 US9067917, 100::US9682971, 100

SMILES: OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccoc2)CCCC1

InChI Key: InChIKey=IPDSMHMBGGUXND-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165065 (US9067917, 100 | US9682971, 100) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccoc2)CCCC1 Show InChI InChI=1S/C35H31N3O4/c39-34(40)35(15-3-4-16-35)20-33-37-31-19-29(42-23-28-11-10-25-7-1-2-9-30(25)36-28)12-13-32(31)38(33)21-24-6-5-8-26(18-24)27-14-17-41-22-27/h1-2,5-14,17-19,22H,3-4,15-16,20-21,23H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165065 (US9067917, 100 | US9682971, 100) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccoc2)CCCC1 Show InChI InChI=1S/C35H31N3O4/c39-34(40)35(15-3-4-16-35)20-33-37-31-19-29(42-23-28-11-10-25-7-1-2-9-30(25)36-28)12-13-32(31)38(33)21-24-6-5-8-26(18-24)27-14-17-41-22-27/h1-2,5-14,17-19,22H,3-4,15-16,20-21,23H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair