BDBM165107 US9067917, 142::US9682971, 142

SMILES: OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccn[nH]2)CCCC1

InChI Key: InChIKey=NGQHPDDBVYCBPP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165107 (US9067917, 142 | US9682971, 142) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccn[nH]2)CCCC1 Show InChI InChI=1S/C34H31N5O3/c40-33(41)34(15-3-4-16-34)20-32-37-30-19-27(42-22-26-11-10-24-7-1-2-9-28(24)36-26)12-13-31(30)39(32)21-23-6-5-8-25(18-23)29-14-17-35-38-29/h1-2,5-14,17-19H,3-4,15-16,20-22H2,(H,35,38)(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165107 (US9067917, 142 | US9682971, 142) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2ccn[nH]2)CCCC1 Show InChI InChI=1S/C34H31N5O3/c40-33(41)34(15-3-4-16-34)20-32-37-30-19-27(42-22-26-11-10-24-7-1-2-9-28(24)36-26)12-13-31(30)39(32)21-23-6-5-8-25(18-23)29-14-17-35-38-29/h1-2,5-14,17-19H,3-4,15-16,20-22H2,(H,35,38)(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair