BDBM165130 US9067917, 165::US9682971, 165

SMILES: CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(cc1)S(N)(=O)=O)C(O)=O

InChI Key: InChIKey=QMERBKLCPFHWQD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165130 (US9067917, 165 | US9682971, 165) Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(cc1)S(N)(=O)=O)C(O)=O Show InChI InChI=1S/C35H32N4O5S/c1-35(2,34(40)41)20-33-38-31-19-28(44-22-27-13-10-25-7-3-4-9-30(25)37-27)14-17-32(31)39(33)21-23-6-5-8-26(18-23)24-11-15-29(16-12-24)45(36,42)43/h3-19H,20-22H2,1-2H3,(H,40,41)(H2,36,42,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165130 (US9067917, 165 | US9682971, 165) Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(cc1)S(N)(=O)=O)C(O)=O Show InChI InChI=1S/C35H32N4O5S/c1-35(2,34(40)41)20-33-38-31-19-28(44-22-27-13-10-25-7-3-4-9-30(25)37-27)14-17-32(31)39(33)21-23-6-5-8-26(18-23)24-11-15-29(16-12-24)45(36,42)43/h3-19H,20-22H2,1-2H3,(H,40,41)(H2,36,42,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair