BDBM165133 US9067917, 168::US9682971, 168

SMILES: CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1)C(O)=O

InChI Key: InChIKey=KQMKICGSFJELOJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165133 (US9067917, 168 | US9682971, 168) Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1)C(O)=O Show InChI InChI=1S/C36H34N4O5S/c1-36(2,35(41)42)21-34-38-32-20-30(45-23-29-16-13-26-8-4-5-10-31(26)37-29)17-18-33(32)40(34)22-24-7-6-9-27(19-24)25-11-14-28(15-12-25)39-46(3,43)44/h4-20,39H,21-23H2,1-3H3,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165133 (US9067917, 168 | US9682971, 168) Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1)C(O)=O Show InChI InChI=1S/C36H34N4O5S/c1-36(2,35(41)42)21-34-38-32-20-30(45-23-29-16-13-26-8-4-5-10-31(26)37-29)17-18-33(32)40(34)22-24-7-6-9-27(19-24)25-11-14-28(15-12-25)39-46(3,43)44/h4-20,39H,21-23H2,1-3H3,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair