BDBM165738 US9067922, 72

SMILES: Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(F)c(cc3F)C#N)c(c2)C#N)nc1

InChI Key: InChIKey=BWLGANIIOSHCFT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM165738 (US9067922, 72) Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(F)c(cc3F)C#N)c(c2)C#N)nc1 Show InChI InChI=1S/C19H9F3N4O3S/c20-13-1-4-19(25-10-13)26-30(27,28)14-2-3-17(12(5-14)9-24)29-18-7-15(21)11(8-23)6-16(18)22/h1-7,10H,(H,25,26)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Limited US Patent					Assay Description Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...				US Patent US9067922 (2015) BindingDB Entry DOI: 10.7270/Q2VQ31F0
					More data for this Ligand-Target Pair