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SMILES: Fc1cnc(NS(=O)(=O)c2ccc(Oc3ccc(C#N)c(Cl)c3)c(c2)C#N)nc1

InChI Key: InChIKey=GZDUUAZILLHYPR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM165756
PNG
(US9067922, 91)
Show SMILES Fc1cnc(NS(=O)(=O)c2ccc(Oc3ccc(C#N)c(Cl)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C18H9ClFN5O3S/c19-16-6-14(2-1-11(16)7-21)28-17-4-3-15(5-12(17)8-22)29(26,27)25-18-23-9-13(20)10-24-18/h1-6,9-10H,(H,23,24,25)
KEGG

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PC cid
PC sid
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Similars
US Patent
n/an/a 1.95E+3n/an/an/an/a7.4n/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...

US Patent US9067922 (2015)


BindingDB Entry DOI: 10.7270/Q2VQ31F0
More data for this
Ligand-Target Pair