BDBM16616 6-{[(2,3-dichlorophenyl)methane]sulfonyl}-2,3-dihydropyridazin-3-one::Benzyl-Substituted Sulfonylpyridazinone, 15e

SMILES: Clc1cccc(CS(=O)(=O)c2ccc(=O)[nH]n2)c1Cl

InChI Key: InChIKey=ZAIAVBMBDRUAAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM16616 (6-{[(2,3-dichlorophenyl)methane]sulfonyl}-2,3-dihy...) Show SMILES Clc1cccc(CS(=O)(=O)c2ccc(=O)[nH]n2)c1Cl Show InChI InChI=1S/C11H8Cl2N2O3S/c12-8-3-1-2-7(11(8)13)6-19(17,18)10-5-4-9(16)14-15-10/h1-5H,6H2,(H,14,16)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...				J Med Chem 48: 6326-39 (2005) Article DOI: 10.1021/jm050462t BindingDB Entry DOI: 10.7270/Q2RN363Z
					More data for this Ligand-Target Pair