BDBM167818 US9073922, 314

SMILES: CS(=O)(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2ccccc2)n1

InChI Key: InChIKey=KWNXZADHKDJCIJ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167818 (US9073922, 314) Show SMILES CS(=O)(=O)N1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cncc(NCc2ccccc2)n1 Show InChI InChI=1S/C24H26N6O2S/c1-33(31,32)30-11-8-18(9-12-30)21-13-20-19(7-10-26-24(20)29-21)22-15-25-16-23(28-22)27-14-17-5-3-2-4-6-17/h2-7,10,13,15-16,18H,8-9,11-12,14H2,1H3,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair