BDBM167839 US9073922, 335

SMILES: C(Nc1cncc(n1)-c1ccnc2[nH]c(cc12)C1=CCNCC1)c1ccccc1

InChI Key: InChIKey=PHSZOCMREOEYHD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167839 (US9073922, 335) Show SMILES C(Nc1cncc(n1)-c1ccnc2[nH]c(cc12)C1=CCNCC1)c1ccccc1 |t:20| Show InChI InChI=1S/C23H22N6/c1-2-4-16(5-3-1)13-27-22-15-25-14-21(28-22)18-8-11-26-23-19(18)12-20(29-23)17-6-9-24-10-7-17/h1-6,8,11-12,14-15,24H,7,9-10,13H2,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
					More data for this Ligand-Target Pair