BDBM167931 1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)-1H-pyrazol-3(2H)-one (1)

SMILES: Cc1c(C(=O)CS(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C

InChI Key: InChIKey=XAUUYFMHCZGINF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase-IV (DDP-4) (Homo sapiens (Human))	BDBM167931 (1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)...) Show SMILES Cc1c(C(=O)CS(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C19H18N2O4S/c1-14-18(17(22)13-26(24,25)16-11-7-4-8-12-16)19(23)21(20(14)2)15-9-5-3-6-10-15/h3-12H,13H2,1-2H3	PDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	25
Cairo University					Assay Description A 200-µL reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...				Chem Biol Drug Des 86: 1292-303 (2015) Article DOI: 10.1111/cbdd.12593 BindingDB Entry DOI: 10.7270/Q2M32THN
					More data for this Ligand-Target Pair