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SMILES: Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCOCC1

InChI Key: InChIKey=HHGUCXDDCLOWPZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168236 (US9669031, 64 8-chloro-6-(pyrimidin-4-ylamino)-2&#...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCOCC1 Show InChI InChI=1S/C15H14ClN5O3/c16-9-7-10(19-11-1-4-17-8-18-11)14(23)21-12(9)13(22)20-15(21)2-5-24-6-3-15/h1,4,7-8H,2-3,5-6H2,(H,20,22)(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168236 (US9669031, 64 8-chloro-6-(pyrimidin-4-ylamino)-2&#...) Show SMILES Clc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCOCC1 Show InChI InChI=1S/C15H14ClN5O3/c16-9-7-10(19-11-1-4-17-8-18-11)14(23)21-12(9)13(22)20-15(21)2-5-24-6-3-15/h1,4,7-8H,2-3,5-6H2,(H,20,22)(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
					More data for this Ligand-Target Pair