null

SMILES: CC1(NC(=O)c2c(Cl)cc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n12)c1ccccc1

InChI Key: InChIKey=QAIVUOYXMDYZIM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168269 (US9669031, 97 N-(6-((8-chloro-3-methyl-1,5-dioxo-3...) Show SMILES CC1(NC(=O)c2c(Cl)cc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n12)c1ccccc1 Show InChI InChI=1S/C22H19ClN6O3/c1-22(13-5-3-2-4-6-13)28-20(31)18-14(23)9-15(21(32)29(18)22)26-16-10-17(25-11-24-16)27-19(30)12-7-8-12/h2-6,9-12H,7-8H2,1H3,(H,28,31)(H2,24,25,26,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168269 (US9669031, 97 N-(6-((8-chloro-3-methyl-1,5-dioxo-3...) Show SMILES CC1(NC(=O)c2c(Cl)cc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n12)c1ccccc1 Show InChI InChI=1S/C22H19ClN6O3/c1-22(13-5-3-2-4-6-13)28-20(31)18-14(23)9-15(21(32)29(18)22)26-16-10-17(25-11-24-16)27-19(30)12-7-8-12/h2-6,9-12H,7-8H2,1H3,(H,28,31)(H2,24,25,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
					More data for this Ligand-Target Pair