BDBM168485 US9675593, 46
SMILES: Fc1ccc(cc1)-c1cn(-c2ccc(OC(F)(F)F)cc2)c(=O)c2nccnc12
InChI Key: InChIKey=NUVAQHXEEVRJJI-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 (Homo sapiens (Human)) | BDBM168485 (US9675593, 46) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After... | US Patent US9675593 (2017) BindingDB Entry DOI: 10.7270/Q2319T24 | |||||||||||
More data for this Ligand-Target Pair |