null

SMILES: Oc1ccc2cc(ccc2c1)C(=O)N1CCC[C@@H]1c1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1

InChI Key: InChIKey=ZXRGWEIYHJUQPL-LITSAYRRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 169597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169597 (US9079880, 130) Show SMILES Oc1ccc2cc(ccc2c1)C(=O)N1CCC[C@@H]1c1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1 |r| Show InChI InChI=1S/C33H34N4O4S/c38-27-10-8-21-17-25(7-6-22(21)19-27)32(40)37-12-2-5-29(37)23-3-1-4-24(18-23)31(39)35-33-34-28-11-9-26(20-30(28)42-33)36-13-15-41-16-14-36/h1,3-4,6-8,10,17-19,26,29,38H,2,5,9,11-16,20H2,(H,34,35,39)/t26-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169597 (US9079880, 130) Show SMILES Oc1ccc2cc(ccc2c1)C(=O)N1CCC[C@@H]1c1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1 |r| Show InChI InChI=1S/C33H34N4O4S/c38-27-10-8-21-17-25(7-6-22(21)19-27)32(40)37-12-2-5-29(37)23-3-1-4-24(18-23)31(39)35-33-34-28-11-9-26(20-30(28)42-33)36-13-15-41-16-14-36/h1,3-4,6-8,10,17-19,26,29,38H,2,5,9,11-16,20H2,(H,34,35,39)/t26-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair