BDBM170155 4-Methoxy-10-((1-((3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)methyl)-1H-1,2,3-triazol-4-yl)methyl)acridin-9(10H)-one (10f)

SMILES: COc1ccc(cc1)-c1noc(Cn2cc(Cn3c4ccccc4c(=O)c4cccc(OC)c34)nn2)n1

InChI Key: InChIKey=WPTNXWDKDSFRDK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 170155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM170155 (4-Methoxy-10-((1-((3-(4-methoxyphenyl)-1,2,4-oxadi...) Show SMILES COc1ccc(cc1)-c1noc(Cn2cc(Cn3c4ccccc4c(=O)c4cccc(OC)c34)nn2)n1 Show InChI InChI=1S/C27H22N6O4/c1-35-19-12-10-17(11-13-19)27-28-24(37-30-27)16-32-14-18(29-31-32)15-33-22-8-4-3-6-20(22)26(34)21-7-5-9-23(36-2)25(21)33/h3-14H,15-16H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	25
Tehran University of Medical Sciences					Assay Description To evaluate in vitro AChE activity, modified Ellman's method was performed using a 96-well plate reader (BioTek ELx808, Highland Park, IL, USA). ...				Chem Biol Drug Des 86: 1425-32 (2015) Article DOI: 10.1111/cbdd.12609 BindingDB Entry DOI: 10.7270/Q2SN07QM
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM170155 (4-Methoxy-10-((1-((3-(4-methoxyphenyl)-1,2,4-oxadi...) Show SMILES COc1ccc(cc1)-c1noc(Cn2cc(Cn3c4ccccc4c(=O)c4cccc(OC)c34)nn2)n1 Show InChI InChI=1S/C27H22N6O4/c1-35-19-12-10-17(11-13-19)27-28-24(37-30-27)16-32-14-18(29-31-32)15-33-22-8-4-3-6-20(22)26(34)21-7-5-9-23(36-2)25(21)33/h3-14H,15-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	25
Tehran University of Medical Sciences					Assay Description To evaluate in vitro AChE activity, modified Ellman's method was performed using a 96-well plate reader (BioTek ELx808, Highland Park, IL, USA). ...				Chem Biol Drug Des 86: 1425-32 (2015) Article DOI: 10.1111/cbdd.12609 BindingDB Entry DOI: 10.7270/Q2SN07QM
					More data for this Ligand-Target Pair