BDBM172409 US9090618, ZA28::US9598411, Ref. No. ZA28

SMILES: CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1

InChI Key: InChIKey=NOZKLXPHSNTUKW-UHFFFAOYSA-N

Data: 8 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 172409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	22.4	-10.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 ug membrane protein in a fin...				US Patent US9090618 (2015) BindingDB Entry DOI: 10.7270/Q2G73CGB
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	22.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...				US Patent US9598411 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V9S
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	26.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...				US Patent US9598411 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V9S
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	26.2	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose displacement assays used 0.4-0.8 nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 μg membrane protein (recombinant kappa opioid re...				US Patent US9090618 (2015) BindingDB Entry DOI: 10.7270/Q2G73CGB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.47E+3	-7.64	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays were conducted using freshly thawed membranes expressing human mu-receptors (Perkin Elmer, Shelton, Conn.). Radioligand do...				US Patent US9090618 (2015) BindingDB Entry DOI: 10.7270/Q2G73CGB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US9598411 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V9S
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...				US Patent US9598411 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V9S
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM172409 (US9090618, ZA28 | US9598411, Ref. No. ZA28) Show SMILES CONC(=N)\N=c1/[nH]c2ccccc2n1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H34N6O/c1-29-26-21(23)25-22-24-19-11-7-8-12-20(19)28(22)18-13-15-27(16-14-18)17-9-5-3-2-4-6-10-17/h7-8,11-12,17-18H,2-6,9-10,13-16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg membrane protein (recombinant delta opioid ...				US Patent US9090618 (2015) BindingDB Entry DOI: 10.7270/Q2G73CGB
					More data for this Ligand-Target Pair