BDBM17246 3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-4,5-bis[(propylamino)methyl]thiophene-2-carboxamide::thiophene-containing non-amidine inhibitor, 48

SMILES: CCCNCc1sc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c(Cl)c1CNCCC

InChI Key: InChIKey=FWTSOYMNLPZPPX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM17246 (3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...) Show SMILES CCCNCc1sc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c(Cl)c1CNCCC Show InChI InChI=1S/C26H29Cl3N4O2S/c1-3-11-30-14-20-22(15-31-12-4-2)36-24(23(20)29)26(35)33-21-10-7-17(28)13-19(21)25(34)32-18-8-5-16(27)6-9-18/h5-10,13,30-31H,3-4,11-12,14-15H2,1-2H3,(H,32,34)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex					Assay Description The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...				Bioorg Med Chem 15: 2127-46 (2007) Article DOI: 10.1016/j.bmc.2006.12.019 BindingDB Entry DOI: 10.7270/Q2MS3R1T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM17246 (3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...) Show SMILES CCCNCc1sc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c(Cl)c1CNCCC Show InChI InChI=1S/C26H29Cl3N4O2S/c1-3-11-30-14-20-22(15-31-12-4-2)36-24(23(20)29)26(35)33-21-10-7-17(28)13-19(21)25(34)32-18-8-5-16(27)6-9-18/h5-10,13,30-31H,3-4,11-12,14-15H2,1-2H3,(H,32,34)(H,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex					Assay Description The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...				Bioorg Med Chem 15: 2127-46 (2007) Article DOI: 10.1016/j.bmc.2006.12.019 BindingDB Entry DOI: 10.7270/Q2MS3R1T
					More data for this Ligand-Target Pair