BDBM173603 (E)-2-(E)-((1H-Indole-3-yl)methylene)hydrazono)thiazolidine-4-one (16)

SMILES: O=C1CS\C(N1)=N\N=C/C1C=Nc2ccccc12

InChI Key: InChIKey=LPGSMULPQCPMAP-NSIKDUERSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urea Amidohydrolase Subunit alpha (Bacillus pasteurii)	BDBM173603 ((E)-2-(E)-((1H-Indole-3-yl)methylene)hydrazono)thi...) Show SMILES O=C1CS\C(N1)=N\N=C/C1C=Nc2ccccc12 |c:11| Show InChI InChI=1S/C12H10N4OS/c17-11-7-18-12(15-11)16-14-6-8-5-13-10-4-2-1-3-9(8)10/h1-6,8H,7H2,(H,15,16,17)/b14-6-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.14E+4	n/a	n/a	n/a	n/a	7.0	n/a
Hazara University					Assay Description This assay was modified from Berthelot assay and was employed for the determination of urease activity. The assay is based on the hydrolysis of urea ...				Bioorg Chem 63: 123-31 (2015) Article DOI: 10.1016/j.bioorg.2015.10.005 BindingDB Entry DOI: 10.7270/Q2H130RM
					More data for this Ligand-Target Pair