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SMILES: NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(NCCN2CCCCC2)cc1

InChI Key: InChIKey=MKSPZKFAEHWFCN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173978   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM173978
PNG
(US9102637, 13)
Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(NCCN2CCCCC2)cc1
Show InChI InChI=1S/C28H30N6O2S/c29-25(35)24-27(37-28(32-24)31-23-13-8-19-6-2-3-7-21(19)18-23)33-26(36)20-9-11-22(12-10-20)30-14-17-34-15-4-1-5-16-34/h2-3,6-13,18,30H,1,4-5,14-17H2,(H2,29,35)(H,31,32)(H,33,36)
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Similars
US Patent
n/an/a 8n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair