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SMILES: NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=WNZBWYKGYNFQPE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173983   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM173983
PNG
(US9102637, 18)
Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C26H25N5O3S/c27-23(32)22-25(35-26(29-22)28-21-10-9-18-3-1-2-4-20(18)15-21)30-24(33)19-7-5-17(6-8-19)16-31-11-13-34-14-12-31/h1-10,15H,11-14,16H2,(H2,27,32)(H,28,29)(H,30,33)
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Similars
US Patent
n/an/a 8.60n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair