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SMILES: NCc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O

InChI Key: InChIKey=BHOAQQIONKMFFB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173988   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM173988
PNG
(US9102637, 23)
Show SMILES NCc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O
Show InChI InChI=1S/C22H19N5O2S/c23-12-13-5-7-15(8-6-13)20(29)27-21-18(19(24)28)26-22(30-21)25-17-10-9-14-3-1-2-4-16(14)11-17/h1-11H,12,23H2,(H2,24,28)(H,25,26)(H,27,29)
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Similars
US Patent
n/an/a 5.30n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair