BDBM174081 US9102637, 116

SMILES: NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CCO)cc1

InChI Key: InChIKey=NBQJGJIWUJGULL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174081 (US9102637, 116) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CCO)cc1 Show InChI InChI=1S/C23H20N4O3S/c24-20(29)19-22(27-21(30)16-7-5-14(6-8-16)11-12-28)31-23(26-19)25-18-10-9-15-3-1-2-4-17(15)13-18/h1-10,13,28H,11-12H2,(H2,24,29)(H,25,26)(H,27,30)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair