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SMILES: CC#CC(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O

InChI Key: InChIKey=BFXWQOVAMPODFG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174130   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM174130
PNG
(US9102637, 165)
Show SMILES CC#CC(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O
Show InChI InChI=1S/C18H14N4O2S/c1-2-5-14(23)21-17-15(16(19)24)22-18(25-17)20-13-9-8-11-6-3-4-7-12(11)10-13/h3-4,6-10H,1H3,(H2,19,24)(H,20,22)(H,21,23)
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Similars
US Patent
n/an/a 4.40n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair