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SMILES: NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cnnn2)cc1

InChI Key: InChIKey=PVYWRGKNATVPLE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174170   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM174170
PNG
(US9102637, 205)
Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cnnn2)cc1
Show InChI InChI=1S/C23H18N8O2S/c24-20(32)19-22(28-21(33)16-7-5-14(6-8-16)12-31-13-25-29-30-31)34-23(27-19)26-18-10-9-15-3-1-2-4-17(15)11-18/h1-11,13H,12H2,(H2,24,32)(H,26,27)(H,28,33)
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Similars
US Patent
n/an/a 5.90n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair