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SMILES: NC1CCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)CC1

InChI Key: InChIKey=VTYBXTOFABINOL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174187   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM174187
PNG
(US9102637, 222)
Show SMILES NC1CCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)CC1
Show InChI InChI=1S/C27H28N6O2S/c28-21-11-13-33(14-12-21)16-17-5-7-19(8-6-17)25(35)32-26-23(24(29)34)31-27(36-26)30-22-10-9-18-3-1-2-4-20(18)15-22/h1-10,15,21H,11-14,16,28H2,(H2,29,34)(H,30,31)(H,32,35)
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Similars
US Patent
n/an/a 1.30n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair