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SMILES: Cc1nccn1Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O

InChI Key: InChIKey=BDXUSEPHZGIROK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174202   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TRAF2 and NCK-interacting protein kinase


(Homo sapiens (Human))		BDBM174202
PNG
(US9102637, 237)
Show SMILES Cc1nccn1Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O
Show InChI InChI=1S/C26H22N6O2S/c1-16-28-12-13-32(16)15-17-6-8-19(9-7-17)24(34)31-25-22(23(27)33)30-26(35-25)29-21-11-10-18-4-2-3-5-20(18)14-21/h2-14H,15H2,1H3,(H2,27,33)(H,29,30)(H,31,34)
PDB

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Similars
US Patent
n/an/a 2.30n/an/an/an/a7.525



CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent


Assay Description
The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...

US Patent US9102637 (2015)


BindingDB Entry DOI: 10.7270/Q2KS6Q9T
More data for this
Ligand-Target Pair