BDBM174478 US9102670, 4l

SMILES: CNCc1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C

InChI Key: InChIKey=XVCQFXJYGXGGGT-ROUUACIJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM174478 (US9102670, 4l) Show SMILES CNCc1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C25H32N6O2/c1-17-15-32-11-9-30(17)24-21-7-8-22(20-6-4-5-19(13-20)14-26-3)27-23(21)28-25(29-24)31-10-12-33-16-18(31)2/h4-8,13,17-18,26H,9-12,14-16H2,1-3H3/t17-,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	25
KUDOS PHARMACEUTICALS LIMITED US Patent					Assay Description The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...				US Patent US9102670 (2015) BindingDB Entry DOI: 10.7270/Q26M35MZ
					More data for this Ligand-Target Pair