BDBM174695 US9102670, 18ck

SMILES: COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N(CCO)CCO)N1CCOC[C@@H]1C

InChI Key: InChIKey=SNVUTZRJNVDYGR-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM174695 (US9102670, 18ck) Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N(CCO)CCO)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C24H31N5O5/c1-16-15-34-12-9-29(16)23-19-4-5-20(17-3-6-21(33-2)18(13-17)14-32)25-22(19)26-24(27-23)28(7-10-30)8-11-31/h3-6,13,16,30-32H,7-12,14-15H2,1-2H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	25
KUDOS PHARMACEUTICALS LIMITED US Patent					Assay Description The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...				US Patent US9102670 (2015) BindingDB Entry DOI: 10.7270/Q26M35MZ
					More data for this Ligand-Target Pair