BDBM174699 US9102670, 18co

SMILES: COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCNC(=O)C1C)N1CCOC[C@@H]1C

InChI Key: InChIKey=ZKECRUOSALDTQL-VYRBHSGPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM174699 (US9102670, 18co) Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCNC(=O)C1C)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C25H30N6O4/c1-15-14-35-11-10-30(15)23-19-5-6-20(17-4-7-21(34-3)18(12-17)13-32)27-22(19)28-25(29-23)31-9-8-26-24(33)16(31)2/h4-7,12,15-16,32H,8-11,13-14H2,1-3H3,(H,26,33)/t15-,16?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	25
KUDOS PHARMACEUTICALS LIMITED US Patent					Assay Description The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...				US Patent US9102670 (2015) BindingDB Entry DOI: 10.7270/Q26M35MZ
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