BDBM175053 US9688678, 16 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1-(4-fluorophenyl)sulfonyl-3-[2-(1-methyl-4-piperidyl)-2,6-diazaspiro[3.3]heptan-6-yl]-2-oxo-indoline-5-carbonitrile

SMILES: CCOc1ccc(OC)cc1C1(C2C=C(C=CC2N(C1=O)S(=O)(=O)c1cc(F)ccn1)C#N)N1CC2(CN(C2)C2CCN(C)CC2)C1

InChI Key: InChIKey=IGGGZXIJXOKGOU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1b receptor (V1b) (Homo sapiens (Human))	BDBM175053 (US9688678, 16 (+-)-3-(2-ethoxy-5-methoxy-phenyl)-1...) Show SMILES CCOc1ccc(OC)cc1C1(C2C=C(C=CC2N(C1=O)S(=O)(=O)c1cc(F)ccn1)C#N)N1CC2(CN(C2)C2CCN(C)CC2)C1 |c:14,16| Show InChI InChI=1S/C34H39FN6O5S/c1-4-46-30-8-6-26(45-3)17-28(30)34(40-21-33(22-40)19-39(20-33)25-10-13-38(2)14-11-25)27-15-23(18-36)5-7-29(27)41(32(34)42)47(43,44)31-16-24(35)9-12-37-31/h5-9,12,15-17,25,27,29H,4,10-11,13-14,19-22H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	-9.90	n/a	n/a	n/a	n/a	n/a	7.4	25
AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu...				US Patent US9688678 (2017) BindingDB Entry DOI: 10.7270/Q2SN0740
					More data for this Ligand-Target Pair