null
SMILES: CCOc1ccc(OC)cc1C1(C2C=C(C=CC2N(C1=O)S(=O)(=O)c1ccc(OC)cn1)C#N)N1CC2(CN(C2)N2CCN(C)CC2)C1
InChI Key: InChIKey=NMKPKGYCGFHNBI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1b receptor (Homo sapiens (Human)) | BDBM175055 (US9688678, 17B (+)-3-(2-ethoxy-5-methoxy-phenyl)-1...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <1 | <-12.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)). The incu... | US Patent US9688678 (2017) BindingDB Entry DOI: 10.7270/Q2SN0740 | |||||||||||
More data for this Ligand-Target Pair |