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SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3nsc(n3)-c3ccccc3)cc(OC)cc2o1

InChI Key: InChIKey=WBIIJNUNSLZONO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (Homo sapiens (Human))	BDBM175974 (US10047103, 7 | US9688695, 7) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nsc(n3)-c3ccccc3)cc(OC)cc2o1 Show InChI InChI=1S/C23H17N5O4S2/c1-29-14-8-17(31-12-20-25-21(34-27-20)13-6-4-3-5-7-13)15-10-19(32-18(15)9-14)16-11-28-22(24-16)33-23(26-28)30-2/h3-11H,12H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...				US Patent US9688695 (2017) BindingDB Entry DOI: 10.7270/Q28K777N
					More data for this Ligand-Target Pair
Proteinase-activated receptor 4 (Homo sapiens (Human))	BDBM175974 (US10047103, 7 | US9688695, 7) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nsc(n3)-c3ccccc3)cc(OC)cc2o1 Show InChI InChI=1S/C23H17N5O4S2/c1-29-14-8-17(31-12-20-25-21(34-27-20)13-6-4-3-5-7-13)15-10-19(32-18(15)9-14)16-11-28-22(24-16)33-23(26-28)30-2/h3-11H,12H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite de Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US10047103 (2018) BindingDB Entry DOI: 10.7270/Q2QF8VWN
					More data for this Ligand-Target Pair