BDBM17620 5,6-disubstituted anthranilic acid sulfonamide, 9l::6-[(2-bromo-4-fluorobenzene)sulfonamido]-3-(1H-imidazol-4-yl)-2-methoxybenzoic acid

SMILES: COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1c[nH]cn1

InChI Key: InChIKey=XRCWLPZDFKGZCV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17620 (5,6-disubstituted anthranilic acid sulfonamide, 9l...) Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1c[nH]cn1 Show InChI InChI=1S/C17H13BrFN3O5S/c1-27-16-10(13-7-20-8-21-13)3-4-12(15(16)17(23)24)22-28(25,26)14-5-2-9(19)6-11(14)18/h2-8,22H,1H3,(H,20,21)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 17: 2817-22 (2007) Article DOI: 10.1016/j.bmcl.2007.02.062 BindingDB Entry DOI: 10.7270/Q2PK0DD1
					More data for this Ligand-Target Pair