BDBM17622 2-chloro-3-ethyl-6-[(4-fluorobenzene)sulfonamido]benzoic acid::5,6-disubstituted anthranilic acid sulfonamide, 9n

SMILES: CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1Cl

InChI Key: InChIKey=BVUIAHCNMNDNRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17622 (2-chloro-3-ethyl-6-[(4-fluorobenzene)sulfonamido]b...) Show SMILES CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1Cl Show InChI InChI=1S/C15H13ClFNO4S/c1-2-9-3-8-12(13(14(9)16)15(19)20)18-23(21,22)11-6-4-10(17)5-7-11/h3-8,18H,2H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 17: 2817-22 (2007) Article DOI: 10.1016/j.bmcl.2007.02.062 BindingDB Entry DOI: 10.7270/Q2PK0DD1
					More data for this Ligand-Target Pair