BDBM176573 US9120756, 47

SMILES: COc1c(F)cc(cc1F)C(C)C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F

InChI Key: InChIKey=KNEBMJIZSYUGSW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176573 (US9120756, 47) Show SMILES COc1c(F)cc(cc1F)C(C)C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F Show InChI InChI=1S/C21H17ClF5N3O2/c1-11(12-6-16(23)19(32-2)17(24)7-12)20(31)28-10-15-9-18(21(25,26)27)29-30(15)14-5-3-4-13(22)8-14/h3-9,11H,10H2,1-2H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	-11.0	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair