BDBM177582 US9120769, 6::US9663470, 6
SMILES: COc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1ccc2[nH]cnc2c1
InChI Key:
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM177582 (US9120769, 6 | US9663470, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 296 | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International Gmbh US Patent | Assay Description In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio... | US Patent US9663470 (2017) BindingDB Entry DOI: 10.7270/Q2V40X8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM177582 (US9120769, 6 | US9663470, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 296 | n/a | n/a | n/a | n/a | 6.0 | n/a |
Boehringer-Ingelheim International GmbH US Patent | Assay Description n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation... | US Patent US9120769 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HK9 | |||||||||||
More data for this Ligand-Target Pair |