BDBM177676 US9120771, KHG26757

SMILES: CCOC(C1CNC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=BTTOTVJMLUUAJV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM177676 (US9120771, KHG26757) Show SMILES CCOC(C1CNC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C12H15Cl2NO/c1-2-16-12(9-6-15-7-9)8-3-4-10(13)11(14)5-8/h3-5,9,12,15H,2,6-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	153	n/a	n/a	n/a	n/a	7.4	n/a
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY US Patent					Assay Description NE transporter binding assay for evaluating binding of the compound to the norepinephrine transporter was carried out using human recombinant norepin...				US Patent US9120771 (2015) BindingDB Entry DOI: 10.7270/Q2T72G6Q
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM177676 (US9120771, KHG26757) Show SMILES CCOC(C1CNC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C12H15Cl2NO/c1-2-16-12(9-6-15-7-9)8-3-4-10(13)11(14)5-8/h3-5,9,12,15H,2,6-7H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	97.5	n/a	n/a	n/a	n/a	7.4	n/a
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY US Patent					Assay Description 5-HT transporter binding assay for evaluating binding of the compound to the serotonin transporter was carried out using human recombinant serotonin ...				US Patent US9120771 (2015) BindingDB Entry DOI: 10.7270/Q2T72G6Q
					More data for this Ligand-Target Pair