null

SMILES: Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1

InChI Key: InChIKey=NHRIZCZTVRYRON-UMSFTDKQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177816 (US9120791, Example 34 | US9603854, 34) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C44H44N4O6/c49-35-15-13-33(14-16-35)48(32-10-2-1-3-11-32)44(51)38-25-40(46-17-7-6-12-39(38)46)36-26-41-42(54-23-22-53-41)27-37(36)43(50)47-28-31-9-5-4-8-30(31)24-34(47)29-45-18-20-52-21-19-45/h1-5,8-11,13-16,25-27,34,49H,6-7,12,17-24,28-29H2/t34-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177816 (US9120791, Example 34 | US9603854, 34) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C44H44N4O6/c49-35-15-13-33(14-16-35)48(32-10-2-1-3-11-32)44(51)38-25-40(46-17-7-6-12-39(38)46)36-26-41-42(54-23-22-53-41)27-37(36)43(50)47-28-31-9-5-4-8-30(31)24-34(47)29-45-18-20-52-21-19-45/h1-5,8-11,13-16,25-27,34,49H,6-7,12,17-24,28-29H2/t34-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair