BDBM178014 (Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2(3H)-ylidene)-2-methylbenzamide (3b)

SMILES: Cc1cs\c(=N/C(=O)c2ccccc2C)n1-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=QQIRBBYAKNHRTB-ZZEZOPTASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM178014 ((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...) Show SMILES Cc1cs\c(=N/C(=O)c2ccccc2C)n1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17N3O3S2/c1-12-5-3-4-6-16(12)17(22)20-18-21(13(2)11-25-18)14-7-9-15(10-8-14)26(19,23)24/h3-11H,1-2H3,(H2,19,23,24)/b20-18-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	8.2	n/a
Quaid-i-Azam University					Assay Description The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...				Chem Biol Drug Des 87: 434-43 (2016) Article DOI: 10.1111/cbdd.12675 BindingDB Entry DOI: 10.7270/Q2CZ35X0
					More data for this Ligand-Target Pair