BDBM178093 [7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methanamine (Compound 5)

SMILES: NCC1Cc2cc(F)cc(c2O1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=MWAYPGAGAUFEGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aquaporin-1 (AQP1) (Homo sapiens (Human))	BDBM178093 ([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...) Show SMILES NCC1Cc2cc(F)cc(c2O1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H12Cl2FNO/c16-9-1-2-12(14(17)5-9)13-6-10(18)3-8-4-11(7-19)20-15(8)13/h1-3,5-6,11H,4,7,19H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Institute					Assay Description Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...				Chem Biol Drug Des 87: 794-805 (2016) Article DOI: 10.1111/cbdd.12713 BindingDB Entry DOI: 10.7270/Q2GQ6WHZ
					More data for this Ligand-Target Pair