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BDBM17856 3,5-Pyrazolediamine Inhibitor, 6::4-[(E)-2-(3-chloro-2-methylphenyl)diazen-1-yl]-3-imino-3H-pyrazol-5-amine

SMILES: Cc1c(Cl)cccc1NN=c1c(=N)nnc1=N

InChI Key: InChIKey=ZYPXAIPFRVWNLV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17856   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine Aminopeptidase (MAP)


(Escherichia coli (strain K12))		BDBM17856
PNG
(3,5-Pyrazolediamine Inhibitor, 6 | 4-[(E)-2-(3-chl...)
Show SMILES Cc1c(Cl)cccc1NN=c1c(=N)nnc1=N |(-1.03,8.02,;-.26,6.69,;1.28,6.69,;2.05,8.02,;2.05,5.36,;1.28,4.02,;-.26,4.02,;-1.03,5.36,;-2.57,5.36,;-3.34,4.02,;-4.88,4.02,;-6.13,4.93,;-6.13,6.47,;-7.37,4.02,;-6.9,2.56,;-5.35,2.56,;-4.45,1.31,)|
Show InChI InChI=1S/C10H9ClN6/c1-5-6(11)3-2-4-7(5)14-15-8-9(12)16-17-10(8)13/h2-4,12-14H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 550n/an/an/an/a7.530



The Procter & Gamble Pharmaceuticals



Assay Description
The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...

Proteins 66: 538-46 (2007)


Article DOI: 10.1002/prot.21207
BindingDB Entry DOI: 10.7270/Q2MK6B5Q
More data for this
Ligand-Target Pair