BDBM179302 US9126952, 5

SMILES: C1C[C@H](CN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1ccccc1

InChI Key: InChIKey=MDBRXLWSMNKQIT-LJQANCHMSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179302 (US9126952, 5) Show SMILES C1C[C@H](CN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1ccccc1 |r| Show InChI InChI=1S/C23H26N4O/c1-2-5-18(6-3-1)19-7-4-10-27(16-19)23-21-9-8-20(15-22(21)24-17-25-23)26-11-13-28-14-12-26/h1-3,5-6,8-9,15,17,19H,4,7,10-14,16H2/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair