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SMILES: Fc1ccc(cc1)C(=O)C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1

InChI Key: InChIKey=QLMGEKZPUJMLKW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179313   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA-dependent protein kinase catalytic subunit


(Homo sapiens (Human))		BDBM179313
PNG
(US9126952, 16)
Show SMILES Fc1ccc(cc1)C(=O)C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1
Show InChI InChI=1S/C24H25FN4O2/c25-19-5-3-17(4-6-19)23(30)18-2-1-9-29(15-18)24-21-8-7-20(14-22(21)26-16-27-24)28-10-12-31-13-11-28/h3-8,14,16,18H,1-2,9-13,15H2
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Similars
US Patent
n/an/a 300n/an/an/an/a7.425



Merck Patent GmbH

US Patent


Assay Description
The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...

US Patent US9126952 (2015)


BindingDB Entry DOI: 10.7270/Q2JH3JZ2
More data for this
Ligand-Target Pair