BDBM179319 US9126952, 22

SMILES: COc1cccc(c1)C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1

InChI Key: InChIKey=SXDLOMLBRQHGIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179319 (US9126952, 22) Show SMILES COc1cccc(c1)C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1 Show InChI InChI=1S/C24H28N4O2/c1-29-21-6-2-4-18(14-21)19-5-3-9-28(16-19)24-22-8-7-20(15-23(22)25-17-26-24)27-10-12-30-13-11-27/h2,4,6-8,14-15,17,19H,3,5,9-13,16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair