BDBM179320 US9126952, 23

SMILES: C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)n1ccnc1

InChI Key: InChIKey=IWXSMKCGCBIGOG-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179320 (US9126952, 23) Show SMILES C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)n1ccnc1 Show InChI InChI=1S/C21H26N6O/c1-2-17(13-25-7-5-22-16-25)14-27(6-1)21-19-4-3-18(12-20(19)23-15-24-21)26-8-10-28-11-9-26/h3-5,7,12,15-17H,1-2,6,8-11,13-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair