BDBM179327 US9126952, 30

SMILES: Clc1nc(N2CCCC(Cn3cccc3)C2)c2ccc(cc2n1)N1CCOCC1

InChI Key: InChIKey=SZQNYJJRFVIGJC-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179327 (US9126952, 30) Show SMILES Clc1nc(N2CCCC(Cn3cccc3)C2)c2ccc(cc2n1)N1CCOCC1 Show InChI InChI=1S/C22H26ClN5O/c23-22-24-20-14-18(27-10-12-29-13-11-27)5-6-19(20)21(25-22)28-9-3-4-17(16-28)15-26-7-1-2-8-26/h1-2,5-8,14,17H,3-4,9-13,15-16H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair