BDBM179328 US9126952, 31

SMILES: C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1ncccn1

InChI Key: InChIKey=VWFRJWNGDFPZBI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179328 (US9126952, 31) Show SMILES C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1ncccn1 Show InChI InChI=1S/C22H26N6O/c1-3-17(13-21-23-6-2-7-24-21)15-28(8-1)22-19-5-4-18(14-20(19)25-16-26-22)27-9-11-29-12-10-27/h2,4-7,14,16-17H,1,3,8-13,15H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair