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SMILES: C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1cccs1

InChI Key: InChIKey=QXFFCENPWAUOCR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179330   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA-dependent protein kinase catalytic subunit


(Homo sapiens (Human))		BDBM179330
PNG
(US9126952, 33)
Show SMILES C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1cccs1
Show InChI InChI=1S/C22H26N4OS/c1-3-17(13-19-4-2-12-28-19)15-26(7-1)22-20-6-5-18(14-21(20)23-16-24-22)25-8-10-27-11-9-25/h2,4-6,12,14,16-17H,1,3,7-11,13,15H2
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Similars
US Patent
n/an/a<100n/an/an/an/a7.425



Merck Patent GmbH

US Patent


Assay Description
The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...

US Patent US9126952 (2015)


BindingDB Entry DOI: 10.7270/Q2JH3JZ2
More data for this
Ligand-Target Pair