BDBM179332 US9126952, 35

SMILES: C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1cc2ccccc2s1

InChI Key: InChIKey=RAUFNYDOHVPKJZ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179332 (US9126952, 35) Show SMILES C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)c1cc2ccccc2s1 Show InChI InChI=1S/C26H28N4OS/c1-2-6-25-20(5-1)15-22(32-25)14-19-4-3-9-30(17-19)26-23-8-7-21(16-24(23)27-18-28-26)29-10-12-31-13-11-29/h1-2,5-8,15-16,18-19H,3-4,9-14,17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair