BDBM179334 US9126952, 37

SMILES: C1CN(CCO1)c1ccc2c(ncnc2c1)N1CCC=C(C1)c1cccs1

InChI Key: InChIKey=YSQMISOQQKIXMS-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179334 (US9126952, 37) Show SMILES C1CN(CCO1)c1ccc2c(ncnc2c1)N1CCC=C(C1)c1cccs1 |c:22| Show InChI InChI=1S/C21H22N4OS/c1-3-16(20-4-2-12-27-20)14-25(7-1)21-18-6-5-17(13-19(18)22-15-23-21)24-8-10-26-11-9-24/h2-6,12-13,15H,1,7-11,14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair